Table 2.

Inheritance of Hprt1^Gdf9-Cas9 does not influence genome editing efficiency.

Route of Administration	Hprt1Gdf9-Cas9 inheritance	Embryos or Mice Screened†	Genome Editing Detected	% With Genome Editing	P value*
Pooled Microinjection	Inherited	35	15	43	0.16 (NS)
	Not Inherited	19	6	32
Pooled Electroporation	Inherited	18	7	39	1 (NS)
	Not Inherited	32	12	38

^†Samples for genotyping, all microinjection attempts were from live-born mice and all electroporation attempts were from cultured blastocysts

^*Fisher’s Exact test; NS = not significant