Table 2. Potential candidate genes (with known roles in C. elegans egg laying) and variants in the QTL interval on chromosome III (GWA mapping for egg number in utero).

Potential high-impact variants are predicted to disrupt gene function, for example, through nonsense or frameshift mutations; low impact variants are predicted to have little or no impact on gene function, such as synonymous mutations (Cook et al., 2017).

Gene	Chromosome	Interval (bp)	Number of variants(predicted high impact)	Number of variants(predicted low impact)
pat-2	III	8,818,898–8,825,266	1	2
lin-12	III	9,060,220–9,071,472	0	2
ina-1	III	9,168,072–9,172,802	1	2
lin-52	III	9,824,082–9,824,750	0	1
cbp-2	III	9,923,173–9,924,800	20	11