Table 2. Comparison of biochemical parameters between those with and without AKIN Stage II or III renal impairment.
Parameter | 6 h | 12 h | 24 h | ||||||
---|---|---|---|---|---|---|---|---|---|
No AKI ( N = 16) | AKI ( N = 4) | p -Value | No AKI ( N = 16) | AKI ( N = 3) | p -Value | No AKI ( N = 4) | AKI ( N = 9) | p -Value | |
Median (IQR) | Median (IQR) | Median (IQR) | Median (IQR) | Median (IQR) | Median (IQR) | ||||
Plasma chloride (mmol/L) | 107.5 (105, 110) | 106.5 (100.5, 107) | 0.318 | 108.5 (106, 110.5) | 109 (104, 109) | 0.506 | 109.5 (105, 112) | 106 (96, 108) | 0.203 |
Urinary chloride (mmol/L) | 15 (15, 38) | 15 (15, 30) | 0.398 | 21 (15, 65.5) | 15 (15, 68) | 0.611 | 42.5 (15, 89) | 48 (15, 72) | 0.748 |
Urinary FeNa (fraction) | 0.21 (0.07, 0.33) | 0.23 (0.20, 0.28) | 0.953 | 0.15 (0.05, 0.43) | 0.08 (0.07, 0.09) | 0.758 | 0.09 (0.05, 0.49) | 0.12 (0.08, 0.61) | 0.490 |
Plasma Na (mmol/L) | 143 (140, 144) | 139 (137, 143) | 0.232 | 141 (140, 143) | 140 (136, 145) | 0.588 | 139.5 (137, 142) | 134 (132, 140) | 0.287 |
Urinary SID (mmol/L) | 129.8 (98.1, 151.9) | 92.5 (80.3, 117.7) | 0.173 | 112.5 (82.3, 137.4) | 105.4 (101.4, 133.6) | 0.999 | 82.2 (36.2, 93.5) | 85.6 (16.9, 124.7) | 0.937 |
Urinary NH 4 (mEq/L) | 25 (7, 42) | 38 (17, 42) | 0.476 | 37.5 (21.5, 65.5) | 41.5 (30, 53) | 0.928 | 35 (22, 99) | 57 (6, 73) | 0.727 |
SBE (mmol/L) | −3.3 (−5.7, 1.5) | −0.9 (−3.5, −0.7) | 0.925 | −2.8 (−5.2, −1.2) | 0.5 (−7.0, 1.1) | 0.472 | −2.1 (−5.5, −1.1) | 0.9 (−10.4, 1.6) | 0.692 |
Abbreviations: AKI, acute kidney injury; AKIN, Acute Kidney Injury Network; IQR, interquartile range; SBE, standard base excess; SID, strong ion difference.