Fig. 5.

Combinational therapies markedly enhanced type I IFN production and immune cell infiltration in vivo. (A) The resected tumors were homogenized, and the expression level of Ifnα2 was analyzed by qRT-PCR (n = 3). *p < 0.05 and ***p < 0.001. One-way ANOVA t-test. (B) The resected tumors were homogenized, and the expression level of Ifnβ1 was analyzed by qRT-PCR (n = 3). *p < 0.05 and ***p < 0.001. One-way ANOVA t-test. (C) The resected tumors were homogenized, and the expression level of Cxcl10 resected tumors was analyzed by qRT-PCR (n = 3). *p < 0.05 and ***p < 0.001. One-way ANOVA t-test. (D) The representative results were infiltration of CD11C⁺ DCs and GzmB⁺ immune cells were analyzed by immunofluorescent (n = 3). (E) The density of CD11C⁺ DCs was quantified under high-power-field microscopy (n = 3). *p < 0.05. One-way ANOVA t-test. (F) The density of GzmB⁺ T cells was quantified under high-power-field microscopy (n = 3). The quantitative analysis of the immunofluorescent results. **p < 0.01. One-way ANOVA t-test