TABLE 2.
Virus titers in eye swabs during acute infections of micea
| Virus | Titer (log meanb ± SE)
|
||
|---|---|---|---|
| Day 1 p.i. | Day 2 p.i. | Day 3 p.i. | |
| KOS | 6.2 ± 0.2 (4) | 4.6 ± 0.2 (4) | 4.0 ± 0.2 (4) |
| hTK1 | 6.1 ± 0.1 (2) | 3.7 ± 0.5 (2) | 3.6 ± 0.4 (2) |
| hTK2 | 5.9 ± 0.1 (2) | 4.6 ± 0.4 (2) | 3.4 ± 0.6 (2) |
| hTMPK1 | 5.8 ± 0.1 (2) | 3.2 ± 0.6 (2) | 1.6 ± 1.6 (2) |
| hTMPK2 | 5.8 ± 0.2 (2) | 3.8 ± 0 (2) | 0.4 ± 0.4 (2) |
| hdCK1 | 4.8 ± 0.8 (2) | 3.5 ± 0.6 (2) | 0.7 ± 0 (2) |
| hdCK2 | 6.0 ± 0.3 (2) | 3.3 ± 0.2 (2) | 3.3 ± 0.2 (2) |
| tkLTRZ1 | 6.1 ± 0.1 (4) | 3.7 ± 0.4 (4) | 2.5 ± 0.5 (4) |
a
Mice were inoculated corneally with 2 × 106 PFU of the indicated viruses. Virus replication in the eye was assessed by titrating eye swabs at the time points indicated. The number of samples titrated for each group is shown in parentheses.
b
Calculated by averaging the logs of the titers.