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. 2024 Apr 2;15:2839. doi: 10.1038/s41467-024-46540-0

Fig. 5. Characterization of myeloid cells in DAHND, untreated head/neck and trunk AD, as well as HC samples.

Fig. 5

A UMAP plots of myeloid cell subsets. B Dot plot of canonical markers for respective dendritic cell (DC), Langerhans cell (LC), and macrophage (MP) subsets; coloring denotes expression levels within each cluster (red is high). C Absolute cell counts per cluster across conditions: HC (n = 4), trunk AD (n = 5), head/neck AD (n = 5), and DAHND (n = 6); each dot represents a single donor; data are presented as median with IQR. Statistical significance was calculated using a Kruskal–Wallis test for multiple comparisons followed by a Dunn’s post hoc test. D–H Violin plots of selected genes in myeloid cell clusters; y-axis indicates expression levels. I, J Feature plots of ALOX15 and RARRES2 expression in each disease group. Intensity of expression levels for each cell is color-coded (red) and overlaid onto UMAP plots. K, L Violin plots of selected genes in DC2, DC4, and LC clusters.