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. 2024 Apr 2;15:2839. doi: 10.1038/s41467-024-46540-0

Fig. 6. Langerhans cells express the IL22 inhibitor IL-22BP.

Fig. 6

A–D Representative immunofluorescence images of CD207 and IL-22BP (IL22RA2) in HC skin, trunk AD, head/neck AD, and DAHND; dotted lines in left images denote dermo-epidermal junction. E Quantification of epidermal and dermal CD207+ Langerhans cells; absolute cell counts are given per mm of epidermis. HC (n = 3), trunk AD (n = 4), head/neck AD (n = 5), and DAHND (n = 3); each dot represents a single donor; data are presented as median with IQR. F Ratio of IL-22BP+ CD207+ cells vs. all CD207+ Langerhans cells within the dermis in respective disease groups: HC (n = 3), trunk AD (n = 4), head/neck AD (n = 5), and DAHND (n = 3); each dot represents a single donor; data are presented as median with IQR.