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. 2024 Apr 2;14:7786. doi: 10.1038/s41598-024-57949-4

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Comparison of oral and faecal microbiome compositions. Spearman correlation coefficients were determined comparing the relative abundance of the oral versus faecal bacterial genera in the (A) HV and (B) RRMS samples. Red colour represents a positive association; blue represents a negative association. The horizontal axis represents the faecal composition and the vertical axis represents the oral composition. Statistically significant spearman correlations are indicated by stars: *p < 0.05, **p < 0.01. (C) The numbers of shared genera between oral and faecal flora in HV (upper Venn diagram) and in MS (lower Venn diagram). The middle boxplot represents the number of shared genera per individual.