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Functional metagenomic profiling. PICRUSt2 algorithm was used to infer gene family abundances, presented in count per million reads and group by EC numbers [(A) for Saliva and (C) for Faeces] and by Metacyc pathways [(B) for Saliva and (D) for faeces]. The most differentially abundant gene families between HV and RRMS groups are shown. *FDR < 0.05, **FDR < 0.01, ***FDR < 0.001.
