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. 2024 Mar 20;5:1373759. doi: 10.3389/fpain.2024.1373759

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© 2024 Reed, Berghaus, Reynolds, Holmes, Krikorian, Sakai, Ishikawa and Knych.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Mechanical nociceptive thresholds (°C) (mean ± SD) at from 0 to 96 h following application of zero (placebo), two (LDF), four (MDF) and six (HDF) 100 mcg/h (16.8 mg/patch) matrix patches to healthy adult horses (n = 6).