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. 2024 Mar 20;14:1305262. doi: 10.3389/fonc.2024.1305262

Table 3.

Cox regression examination investigating the impact of clinicopathological variables on patients’ disease-free survival.

Variables Univariable Cox regression Multivariable Cox regression
HR (95% CI) P HR (95% CI) P
Age 0.990 (0.968-1.012) 0.359
Gender (male) 1.067 (0.589-1.934) 0.831
Tumor diameter 2.1647 (1.848-2.495) <0.001 2.214 (1.859-2.637) <0.001
MWA power (High) 0.670 (0.423-1.062) 0.088 0.500 (0.309-0.810) 0.005
Complication 1.129 (0.730-1.746) 0.585
Tumor differentiation (Poor) 6.811 (4.295-10.802) <0.001 3.604 (2.201-5.901) <0.001
Gene mutation
No mutations ref
EGFR mutations 0.112 (0.041-0.306) <0.001 0.144 (0.052-0.395) <0.001
KRAS mutations 0.754 (0.277-2.055) 0.581 0.554 (0.202-1.521) 0.252
Neutrophil 1.325 (1.167-1.505) <0.001
Lymphocyte 0.669 (0.486-0.920) 0.014
Monocyte 1.491 (0.344-6.463) 0.593
Platelet 1.002 (0.999-1.005) 0.283
SIRI (High) 2.878 (1.941-4.266) <0.001 2.391 (1.573-3.635) <0.001

MWA, microwave ablation, EGFR, Epidermal Growth Factor Receptor, KRAS, Kirstenratsarcomaviraloncogenehomolog, SIRI, the ratio of monocyte multiply neutrophil to lymphocyte.