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. 2024 Mar 15;6(2):100360. doi: 10.1016/j.infpip.2024.100360

Table II.

Summary of multi-drug efflux pumps genes, their known variants, and their substrates

Gene Gene variation(s) Substrates
AcrAB-TolC - Benzalkonium chloride [37]; Chlorhexidine [38]; Triclosan [38]; Cetrimide, Aminoglycosides, Tetracycline [42]; Fluroquinolone [43]
CepA - Chlorhexidine [45,46]
oqxAB - Hydrogen peroxide [52]; Norfloxacin, Sodium dodecyl sulphate, Ethidium bromide, Acriflavine, Rhodamine G, Benzalkonium chloride [53]
qacE qacEΔ1 Chlorhexidine [45]; Quaternary ammonium compounds [45]; Benzalkonium bromide [49]
SmvA ΔsmvA Chlorhexidine, Cetrimide, Cetyltrimethylammonium, Hexadecylpyridium chloride monohydrate [55]