In patients who conceived higher-order multiples (HOM) following multiple embryo transfer, foetal reduction can be considered to reduce the risk of maternal complications (Groutz et al., 1996; Anthoulakis et al., 2017; Zipori et al., 2017; Liu et al., 2019; Jin et al., 2020). | Conditional⊕○○○ |
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The transfer of two or more embryos with the intention of performing foetal reduction in case of multiple embryo implantation instead of (e)SET is not recommended (van de Mheen et al., 2015; Kristensen et al., 2022; Wang et al., 2022; Yimin et al., 2022). | Strong⊕○○○ |
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The GDG recommends against the transfer of more than two embryos with foetal reduction after multiple embryo implantation considering the high risks of the procedure. | GPP |