Table 3.
Association between individual component of metabolic risk factors at baseline and risk of depression
| Nonobese | Obese | |||
|---|---|---|---|---|
| No individual metabolic risk factor | Individual metabolic risk factor | No individual metabolic risk factor | Individual metabolic risk factor | |
| Hypertension | ||||
| Events/N (%) | 156/1,689 (9.2%) | 94/701 (13.4%) | 72/532 (13.5%) | 86/475 (18.1%) |
| OR, age– and sex–adjusteda | 1 [Reference] | 1.36 (1.02–1.80) | 1.50 (1.10–2.02) | 1.83 (1.35–2.46) |
| OR, multivariate–adjustedb | 1 [Reference] | 1.23 (0.91–1.65) | 1.35 (0.97–1.86) | 1.56 (1.12–2.16) |
| Diabetes | ||||
| Events/N (%) | 236/2,302 (10.3%) | 14/88 (15.9%) | 136/909 (15.0%) | 22/98 (22.4%) |
| OR, age– and sex–adjusteda | 1 [Reference] | 1.68 (0.88–2.99) | 1.44 (1.14–1.81) | 2.15 (1.26–3.53) |
| OR, multivariate–adjustedb | 1 [Reference] | 1.36 (0.68–2.56) | 1.32 (1.02–1.69) | 1.75 (0.98–3.00) |
| Hypercholesterolemia | ||||
| Events/N (%) | 204/1,990 (10.3%) | 46/400 (11.5%) | 116/794 (14.6%) | 42/213 (19.7%) |
| OR, age– and sex–adjusteda | 1 [Reference] | 1.03 (0.72–1.44) | 1.38 (1.08–1.77) | 1.77 (1.20–2.58) |
| OR, multivariate–adjustedb | 1 [Reference] | 1.04 (0.71–1.48) | 1.34 (1.02–1.75) | 1.28 (0.83–1.94) |
a
Adjusted for age, sex, and mutually for other metabolic risk factors at baseline.
b
Adjusted for age, sex, race/ethnicity, education level, smoking, alcohol consumption, physical activity, cardiovascular diseases, history of psychiatric disorders, CES-D score, and mutually for other metabolic risk factors at baseline.