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. 2023 Nov 18;74(2):335–342. doi: 10.1016/j.identj.2023.10.012

Table 2.

Study characteristics of individual studies.

Study ID No. (M/F) Diagnosis Tooth type Groups No. of drop out Endodontic treatment Evaluation method Evaluation interval/considered interval Observed outcomes
Hakan Arslan PLD-13/4
LD-8/8
Periapical lesions with scores 2 or 3 in accordance with the periapical index Symptomatic mandibular molars LLLT-16
MOCK LASER-17
2 from LLLT
1 from placebo
2 visits using intracanal medicament VAS scale 4, 8, 12, 24, and 48 hours
24 hours, 48 hours, 72 hours
24 hours (P < .05)
Significant
48 hours (P < .05)
Significant
72 hours (P < .05)
Significant
Ozgur Genc Sen PLD-15/21
LD-19/18
Chronic periapical infection (minimum size of lesion, 2*2 mm Single-rooted teeth LLLT-42
MOCK LASER-42
2 in each group A single visit NRS scale 24, 48, and 72 hours
24 hours, 48 hours, 72 hours
48 hours showed significantly less pain in LD group than in PLD group (P < .05) and 72 hours showed insignificant difference (P > .05)
Mahta Fazlyab NR Chronic periapical infection Symptomatic first or second mandibular molars LLLT-18
MOCK
LASER-18
0 A single visit VAS scale 4, 8, 12, and 24 hours and 2, 3, and 7days
24 hours, 48 hours, 72 hours
Both 24 hours and 48 hours showed intense pain in both groups with [mean (SD) = 0.22 (0.54)]

LD, laser disinfection; PLD, pseudo laser disinfection; VAS scale, visual analogue scale; NRS scale, numerical rating scale.