Table 2.
Univariate and multivariate Cox regression analysis of clinicopathologic characteristics associated with OS in the TCGA sample.
| Variable | Univariable | Multivariable | ||
|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | |
| Age (>60 vs. ≤60) | 1.22 (0.864-1.733) | 0.256 | ||
| Child-Pugh grade (B&C vs. A) | 1.64 (0.811-3.330) | 0.168 | ||
| AFP (ng/ml) (>400 vs. ≤400) | 1.06 (0.649-1.731) | 0.817 | ||
| Histologic grade (G3&G4 vs. G1&G2) | 1.11 (0.778-1.592) | 0.557 | ||
| Prothrombin time (>4 vs. ≤4) | 1.31 (0.867-1.984) | 0.200 | ||
| relative family cancer history (Yes vs. No) | 1.19 (0.825-1.716) | 0.352 | ||
| Gender (Male vs. Female) | 1.25 (0.876-1.776) | 0.220 | ||
| Race (Non-Asian vs. Asian) | 1.38 (0.959-1.992) | 0.083 | ||
| Pathologic stage (StageⅢ&Ⅳ vs. StageⅠ&Ⅱ) | 2.46 (1.701-3.568) | <0.001 | 2.44 (1.684-3.536) | <0.001 |
| BMI (>25 vs. ≤25) | 0.82 (0.563-1.181) | 0.280 | ||
| MAP3K14 (High vs. Low) | 1.48 (1.049-2.086) | 0.026 | 1.44 (1.003-2.077) | 0.048 |