Table 3. IRs per 10 000 Person-Years and aHRs of Depression, Anxiety, or Stress-Related Disorders for 1-SD Increase in Carbohydrate, Lipid, and Apolipoprotein Biomarker Levels .
Biomarkera | Depression, anxiety, or stress-related disorders | Depression | Anxiety | Stress-related disorders | ||||
---|---|---|---|---|---|---|---|---|
No. of events (IR) | aHR (95% CI) | No. of events (IR) | aHR (95% CI) | No. of events (IR) | aHR (95% CI) | No. of events (IR) | aHR (95% CI) | |
Glucose | 14 077 (36.4) | 1.07 (1.05-1.09) | 8365 (21.4) | 1.08 (1.05-1.10) | 6599 (16.8) | 1.07 (1.04-1.10) | 4294 (10.9) | 1.07 (1.03-1.11) |
TC | 14 562 (36.5) | 1.02 (1.00-1.04) | 8683 (21.4) | 1.02 (1.00-1.05) | 6816 (16.7) | 1.04 (1.01-1.07) | 4405 (10.8) | 1.00 (0.96-1.03) |
TG | 14 479 (36.3) | 1.07 (1.05-1.09) | 8638 (21.4) | 1.08 (1.06-1.10) | 6776 (16.7) | 1.08 (1.06-1.10) | 4380 (10.7) | 1.07 (1.04-1.11) |
LDL-C | 6207 (34.9) | 1.01 (0.98-1.04) | 3738 (20.8) | 1.00 (0.96-1.03) | 2897 (16.0) | 1.03 (0.99-1.08) | 1779 (9.8) | 0.99 (0.94-1.06) |
HDL-C | 6467 (34.7) | 0.94 (0.92-0.97) | 3854 (20.4) | 0.95 (0.92-0.99) | 3048 (16.1) | 0.92 (0.89-0.96) | 1884 (9.9) | 0.95 (0.90-1.00) |
LDL-C/HDL-C ratio | 5953 (34.9) | 1.03 (1.00-1.07) | 3558 (20.6) | 1.01 (0.98-1.06) | 2790 (16.1) | 1.06 (1.01-1.11) | 1730 (9.9) | 1.04 (0.98-1.10) |
ApoA-I | 5404 (34.4) | 0.97 (0.94-1.00) | 3243 (20.4) | 0.98 (0.94-1.02) | 2560 (16.0) | 0.97 (0.93-1.02) | 1544 (9.6) | 0.97 (0.91-1.03) |
ApoB | 4575 (33.9) | 0.98 (0.94-1.01) | 2707 (19.8) | 0.98 (0.94-1.03) | 2153 (15.7) | 1.00 (0.95-1.06) | 1306 (9.5) | 0.92 (0.85-0.99) |
ApoB/ApoA-I ratio | 3806 (33.1) | 1.01 (0.97-1.05) | 2258 (19.4) | 1.00 (0.96-1.06) | 1808 (15.5) | 1.03 (0.97-1.09) | 1070 (9.1) | 0.98 (0.91-1.06) |
Abbreviations: ApoA-I, apolipoprotein A-I; ApoB, apolipoprotein B; HDL-C, high-density lipoprotein cholesterol; IR, incidence rate; LDL-C, low-density lipoprotein cholesterol; TC, total cholesterol; TG, triglycerides.
Adjusted for age at first blood sampling, sex, fasting status, country of birth, and socioeconomic status.