Table 2.
Effect of I/p injection of fructose (2.75 mM) and TiO2 NPS (100 mg/kg BW) on developmental competence of in-vitro matured mice oocytes (In-vivo study)
| Treatment | n | MII% | MI% | GVBD% | Degenerated% | Activated% |
|---|---|---|---|---|---|---|
| Control (G1) | 168 | 34.05 ± 1.57a# | 20.07 ± 1.16b* | 19.34 ± 3.20a# | 17.74 ± 2.34b$ | 8.80 ± 1.61b$ |
| TiO2 NP (G2) | 160 | 18.97 ± 2.52c$ | 14.84 ± 2.23c$ | 16.59 ± 0.64b$ | 24.35 ± 2.23a# | 25.25 ± 6.05a# |
| TiO2 NP + Fructose (G3) | 142 | 28.31 ± 3.20b* | 22.71 ± 1.85a* | 18.91 ± 3.93a# | 14.11 ± 2.92b* | 15.96 ± 4.04a# |
Means with different superscripts (a, b, c) are different (P < 0.05). Values are presented as means ± SEM
Abbreviations MII = metaphase II; MI = metaphase I, GVBD = germinal vesicle break-down, TiO2 NP = titanium dioxide nanoparticle