Table 2.
The univariate and multivariate analysis for the OS (TCGA-UCEC).
| Characteristics | Total(N) | Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|---|---|
| Hazard ratio (95% CI) | P value* | Hazard ratio (95% CI) | P value* | |||
| Primary therapy outcome | CR&PR&SD | 460 | Reference | NA | ||
| PD | 20 | 7.821 (4.267-14.336) | <0.001 | 4.032 (1.550-10.490) | 0.004 | |
| Residual tumor | R0 | 374 | Reference | NA | ||
| R1&R2 | 38 | 3.101 (1.768-5.440) | <0.001 | 2.751 (1.234-6.135) | 0.013 | |
| Histologic grade | G1 | 98 | Reference | NA | ||
| G3&G2 | 442 | 11.604 (2.855-47.167) | <0.001 | 11.982 (1.612-89.035) | 0.015 | |
| Radiation therapy | Yes | 248 | Reference | NA | ||
| No | 279 | 1.684 (1.092-2.596) | 0.018 | 3.277 (1.743-6.163) | <0.001 | |
| Tumor invasion(%) | <50 | 259 | Reference | NA | ||
| >=50 | 214 | 2.813 (1.744-4.535) | <0.001 | 1.656 (0.838-3.274) | 0.147 | |
| GLS | 551 | 1.296 (1.097-1.532) | 0.002 | 1.384 (1.032-1.855) | 0.030 | |
OS, overall survival; CI, confidence interval; NA, reference group or could not be evaluated. *Compared with each group (Log-Rank test or Omnibus test for univariate, Cox regression analysis with adjusted hazard for multivariate). p<0.05 means statistically significant (highlighted in bold)