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. 2024 Apr 2;28:108. doi: 10.1186/s13054-024-04869-4

Table 2.

Baseline characteristics based on kidney function and trajectories (as described in Fig. 1)

Variable Category All Kidney Function at day 5
Normal throughout Developed new AKI AKI II/III throughout Renal recovery from AKI II/III p-value Missing %
n 137 52 11 51 23
Age 54 [47, 68] 50 [41, 69] 52 [51, 67] 57 [48, 66] 54 [48, 68] 0.776 0.7
Gender Male 91 (66) 34 (65) 6 (55) 38 (75) 13 (57) 0.340
Female 46 (34) 18 (35) 5 (45) 13 (25) 10 (43)
Ethnicity Asian 4 (3) 3 (6) 0 1 (2) 0 0.868 3.6
Black 9 (7) 2 (4) 0 5 (10) 2 (9)
Caucasian 118 (86) 43 (83) 11 (100) 43 (84) 21 (91)
Other 1 (1) 1 (2) 0 0 0
Missing 5 (4) 3 (6) 0 2 (4) 0
Season Summer 68 (50) 27 (52) 6 (55) 20 (39) 15 (65) 0.201 0.0
Winter 69 (50) 25 (48) 5 (45) 31 (61) 8 (35)
CRP (Day 0) [mg/dL] 123 [54, 253] 97 [53, 144] 117 [84, 300] 161 [68, 305] 110 [43, 218] 0.037 11.7
Serum 25(OH)D on day 0 [nmol/L] 18 [10, 31] 20 [12, 34] 32 [14, 40] 14 [9, 26] 19 [9, 35] 0.076 6.6
Serum 1,25(OH)2D on day 0 [pmol/L] 50 [28, 68] 54 [33, 69] 63 [36, 106] 41 [26, 58] 36 [26, 56] 0.069 5.1
Calcium (Day 0) [mmol/L] 1.1 [1.1,1.2] 1.1 [1.1,1.2] 1.1 [1.1,1.2] 1.1 [1.1,1.2] 1.1 [1.1,1.2] 0.833 6.6
APACHE II score (on admission) 18 [14, 21] 14 [12, 17] 15 [12, 16] 21 [19, 23] 20 [17, 24]  < 0.001 0.0
SOFA minus renal score (Day 0) 10 [7, 12] 8 [7, 10] 9 [6, 9] 11 [9, 13] 10 [8, 12]  < 0.001 6.6
ICU mortality 25 (18) 4 (7.7) 1 (9) 18 (35.3) 2 (8.7) 0.002 -
Hospital mortality 31 (23) 5 (9.6) 1 (9) 22 (43.1) 3 (13)  < 0.001 1.5
30-day mortality 31 (23) 5 (9.6) 1 (9) 23 (45.1) 2 (8.7) 0.001 5
Length of stay in ICU 14 [8, 23]] 10 [5, 15] 16 [10, 19] 18 [10, 30] 18 [8, 27] 0.010 29

AKI Acute kidney injury, APACHE Acute physiology and chronic health evaluation, CRP C-reactive protein, ICU Intensive Care Unit, SOFA Sequential Organ Failure Assessment

Significant variables are indicated in bold

Results are reported as number (%), mean (%) or median [interquartile range]