Table 2.

Results of the base case, sensitivity and scenario analysis for the comparison between Intraoperative radiation therapy (IORT) and Intensity-modulated radiation therapy (IMRT). Expected benefits and costs, together with the corresponding ICER, are reported for each case and outcome

	IORT	IMRT	Incremental	ICER
Base case
LYs	8.48	8.48	−0.002	−$426,358
RFLYs	7.92	8.19	−0.27	−$3,733
QALYs	7.69	7.75	−0.05	−$19,095
QARFLYs	7.29	7.53	−0.25	−$4,058
Costs	$1,330	$323	$1,006	–
Sensitivity analysis
IORT lower recurrence
LYs	8.48	8.48	−0.002	−$432,972
RFLYs	8.01	8.19	−0.18	−$5,531
QALYs	7.71	7.75	−0.04	−$25,309
QARFLYs	7.37	7.53	−0.17	−$6,012
Costs	$1,330	$323	$1,006	–
IORT lower metastasis
LYs	8.48	8.48	−0.002	−$566,948
RFLYs	7.99	8.19	−0.20	−$4,939
QALYs	7.71	7.75	−0.04	−$27,438
QARFLYs	7.35	7.53	−0.19	−$5,369
Costs	$1,330	$323	$1,006	–
Scenario analysis
LYs	8.48	8.48	−0.002	−$191,905
RFLYs	7.92	8.19	−0.27	−$1,680
QALYs	7.69	7.75	−0.05	−$8,595
QARFLYs	7.29	7.53	−0.25	−$1,826
Costs	$776	$323	$453	–

Abbreviations LYs = Life years, RFLYs = Recurrence-free life years, QALYs = quality-adjusted life years, QARFLYs = Quality-adjusted recurrence-free life years