Table 1.
Patient and tumor characteristics of 42,403 men with localized prostate cancer stratified by risk group.
| Low- Risk (n=16,171; 39.0%) |
Intermediate -Risk (n=16,990; 40.1%) |
High- Risk (n = 9,242; 20.8%) |
p-value# | ||||
|---|---|---|---|---|---|---|---|
| Age | < 0.001 | ||||||
| Median | 63 | 66 | 69 | ||||
| Range | 34–103 | 33–96 | 36–98 | ||||
|
| |||||||
| Race | < 0.001 | ||||||
| White | 11424 | 70.6% | 11746 | 69.1% | 6096 | 66.0% | |
| Black | 2059 | 12.7% | 2732 | 16.1% | 1500 | 16.2% | |
| Hispanic | 1354 | 8.4% | 1251 | 7.4% | 795 | 8.6% | |
| Asian/Pacific Islander | 653 | 4.0% | 743 | 4.4% | 488 | 5.3% | |
| Native American | 49 | 0.3% | 54 | 0.3% | 40 | 0.4% | |
| Other/Unknown | 632 | 3.9% | 464 | 2.7% | 323 | 3.5% | |
|
| |||||||
| Marital status | < 0.001 | ||||||
| Married | 11115 | 39.0% | 11530 | 67.9% | 5821 | 63.0% | |
| Not married | 3043 | 33.9% | 3690 | 21.7% | 2252 | 24.4% | |
| Unknown | 2013 | 40.7% | 1770 | 10.4% | 1169 | 12.6% | |
|
| |||||||
| County poverty rate | < 0.001 | ||||||
| Highest rate quartile | 3835 | 23.7% | 4177 | 24.6% | 2409 | 26.1% | |
| 3rd quartile | 3984 | 24.6% | 4014 | 23.6% | 2351 | 25.4% | |
| 2nd quartile | 4159 | 25.7% | 4313 | 25.4% | 2316 | 25.1% | |
| Lowest rate quartile | 4191 | 25.9% | 4484 | 26.4% | 2160 | 23.4% | |
| Unknown | 2 | 0.0% | 2 | 0.0% | 6 | 0.0% | |
|
| |||||||
| SEER Registry | < 0.001 | ||||||
| SF/Oakland | 982 | 6.1% | 890 | 5.2% | 503 | 5.4% | |
| Connecticut | 738 | 4.6% | 817 | 4.8% | 452 | 4.9% | |
| Detroit | 924 | 5.7% | 1332 | 7.8% | 524 | 5.7% | |
| Hawaii/Alaska | 183 | 1.1% | 224 | 1.3% | 143 | 1.5% | |
| Iowa | 489 | 3.0% | 709 | 4.2% | 404 | 4.4% | |
| New Mexico | 363 | 2.2% | 392 | 2.3% | 246 | 2.7% | |
| Seattle | 955 | 5.9% | 1059 | 6.2% | 537 | 5.8% | |
| Utah | 547 | 3.4% | 541 | 3.2% | 240 | 2.6% | |
| Atlanta | 600 | 3.7% | 727 | 4.3% | 302 | 3.3% | |
| San Jose-Monterey | 617 | 3.8% | 536 | 3.2% | 287 | 3.1% | |
| Los Angeles | 1337 | 8.3% | 1291 | 7.6% | 732 | 7.9% | |
| CA excluding SF/SJM/LA | 3379 | 20.9% | 3458 | 20.4% | 1949 | 21.1% | |
| Kentucky | 771 | 4.8% | 755 | 4.4% | 522 | 5.6% | |
| Louisiana | 1072 | 6.6% | 1080 | 6.4% | 644 | 7.0% | |
| New Jersey | 2041 | 12.6% | 1786 | 10.5% | 981 | 10.6% | |
| Greater/Rural Georgia | 1173 | 7.3% | 1393 | 8.2% | 776 | 8.4% | |
|
| |||||||
| PSA | < 0.001 | ||||||
| < 10 | 16171 | 100.0% | 12326 | 72.5% | 3462 | 37.5% | |
| 10 to 20 | 0 | 0.0% | 4664 | 27.5% | 1436 | 15.5% | |
| > 20 | 0 | 0.0% | 0 | 0.0% | 3561 | 38.5% | |
| Unknown | 0 | 0.0% | 0 | 0.0% | 783 | 8.5% | |
|
| |||||||
| Gleason score | < 0.001 | ||||||
| 2 to 6 | 16171 | 100.0% | 2740 | 16.1% | 913 | 9.9% | |
| 7 | 0 | 0.0% | 14250 | 83.9% | 1689 | 18.3% | |
| 8 to 10 | 0 | 0.0% | 0 | 0.0% | 6532 | 70.7% | |
| Unknown | 0 | 0.0% | 0 | 0.0% | 108 | 1.2% | |
|
| |||||||
| T-stage | < 0.001 | ||||||
| 1 | 12615 | 78.0% | 10977 | 64.6% | 4594 | 49.7% | |
| 2 | 3556 | 22.0% | 6013 | 35.4% | 3540 | 38.3% | |
| 3 | 0 | 0.0% | 0 | 0.0% | 937 | 10.1% | |
| 4 | 0 | 0.0% | 0 | 0.0% | 103 | 1.1% | |
| Unknown | 0 | 0.0% | 0 | 0.0% | 68 | 0.7% | |
#
Comparison across risk groups. Chi-square statistic for categorical variables and t-test for continuous variables.
SEER = Surveillance, Epidemiology, and End Results; NCCN = National Comprehensive Cancer Network; SF = San Francisco; CA = California; SJM = San Jose-Monterey; LA = Los Angeles