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Antibiotic MIC for daptomycin-nonsusceptible MRSA isolates C4 and C37 at baseline and in 168-h SEV samplesa
| Antibiotic MIC (μg/mL) | ||||
|---|---|---|---|---|
| C4 | C37 | |||
| DAP | CPT | DAP | CPT | |
| Baseline | 4 | 0.5 | 4 | 0.25 |
| Post-SEV model MIC (168-h sample) | ||||
| Growth control | 4 | 0.5 | 4 | 0.25 |
| Intesti13 + Sb-1 | 4 | 0.5 | 4 | 0.25 |
| DAP 10 mg/kg | 4 | 0.5 | 4 | 0.25 |
| DAP 10 mg/kg plus Intesti13 + Sb-1 | 4 | 0.5 | 4 | 0.25 |
| DAP 10 mg/kg plus CPT 600 mg Intesti13 + Sb-1 | 4 | 0.5 | 4 | 0.25 |
SEV, simulated endocardial vegetation; DAP, daptomycin; CPT, ceftaroline.
