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. 2024 Feb 27;68(4):e01663-23. doi: 10.1128/aac.01663-23

TABLE 3.

Patient outcomesa

Unweighted cohort Propensity-score-weighted cohort
Albumin
≤ 2.5 g/dL (N = 34)
Albumin
>2.5 g/dL (N = 103)
P value Albumin
≤2.5 g/dL (N = 34)
Albumin
>2.5 g/dL (N = 103)
P value
Clinical success 26 (76.5%) 95 (92.2%) 0.013 77.8% 91.2% 0.038
 Clinical cure 26 (76.5%) 96 (93.2%) 0.007 77.8% 92.0% 0.024
 Microbiologic cure 29 (85.3%) 97 (94.2%) 0.10 81.9% 93.2% 0.055
Hospital length of stay (days),
median (IQR)
14 (8, 28) 9 (6, 16) 0.009 10 (7, 27) 9 (6, 15) 0.21
ICU Length of stay (days),
median (IQR)
3.5 (2.1, 14.2) 2.5 (1.5, 5.7) 0.088 3.5 (2.0, 13.7) 2.4 (1.3, 5.4) 0.092
Death during hospitalization 5 (14.7%) 0 (0.0%) <0.001 13.5% 0.0% <0.001
Death within 30 days 5 (14.7%) 0 (0.0%) <0.001 13.7% 0.0% <0.001
Death within 60 days 8 (23.5%) 1 (1.0%) <0.001 22.6% 0.8% <0.001
Readmission within 30 days 8 (23.5%) 12 (11.7%) 0.089 31.6% 12.0% 0.008
Adverse effects 0.72 0.60
 Neutropenia 0 (0.0%) 2 (1.9%) 0.0% 3.0%
 Rash or other suspected IgE-mediated allergic reactionb 1 (2.9%) 3 (2.9%) 2.7% 2.6%
 None identified 33 (97.1%) 98 (95.1%) 97.3% 94.4%
a

ICU, intensive care unit; g/dL, grams per deciliter; IQR, interquartile range.

b

Suspected IgE-mediated reactions included hives, urticaria, angioedema, or anaphylaxis.