Table 2.

Overview of intervention delivery described according to the TIDieR guidelines

Brief name	Anti-inflammatory dietary programme	Standard care low-fat dietary programme
WHY	Anti-inflammatory diets targeting systemic inflammation assist in the prevention and management of various chronic diseases.16 Small pilot studies have shown a positive effect of anti-inflammatory diets to improve knee-related symptoms in people with knee osteoarthritis.28	Healthy eating guidelines and dietary advice described in the standard care programme booklet was based on Australian Dietary Guidelines (ADGs).37 68 2–3 dietetic consultations represent usual care for patients referred for dietary management in Australia.37 38
WHAT (MATERIALS)	Participants receive an intervention handbook containing all study details, key anti-inflammatory eating principles, example meal plans, traffic light system of foods encouraged and discouraged, and education (eg, common myths, tips for eating out, shopping tips); complimentary access to the Defeat Diabetes programme app/website; complimentary links to three movies; and a complimentary copy of the book ‘A Fat Lot of Good’.35	Participants receive an educational handbook emphasising ADGs healthy eating principles and are provided links to the online resources from the Eat for Health website (https://www.eatforhealth.gov.au/).
WHAT (PROCEDURES)	Six consultations providing individualised guidance and support to follow an anti-inflammatory eating pattern, emphasising the consumption of fruits, non-starchy vegetables, fish, poultry, red meat, eggs, full-fat dairy, nuts, seeds and extra virgin olive oil. Participants will be encouraged to avoid highly processed foods, refined carbohydrates, added sugar and processed meats.	Three consultations providing general advice and education regarding healthy eating based on the ADGs. The principles focus on consumption of foods from the five food groups, while limiting intake of foods containing saturated fat, added salt, added sugars and alcohol.
WHO PROVIDED	A qualified dietitian or health professional specially trained to deliver all components.	A qualified dietitian or health professional specially trained to deliver all components.
HOW	Delivered with individual support for 12 weeks, after which, participants will be encouraged to sustain the anti-inflammatory diet unsupported up to 6 months. Consultations are one to one.	Delivered with standard healthy eating advice for 12 weeks, after which, participants will be encouraged to sustain the programme unsupported up to 6 months. Consultations are one to one.
WHERE	In-person consultations will occur at La Trobe University Nutrition and Dietetics research laboratory. Additional consultations will occur via telephone/videoconference (eg, Zoom). Participants will integrate the diet principles into their daily consumption of foods and beverages.	In-person consultations will occur at the La Trobe University Nutrition and Dietetics research laboratory. Additional consultations will occur via telephone/videoconference (eg, Zoom). Participants will integrate the diet principles into their daily consumption of foods and beverages.
WHEN AND HOW MUCH	Two in-person consultations at baseline (~45 min) and week 12 (~30 min) Four phone/videoconference follow-up consultations (~30 min) in weeks 2, 4, 6 and 9. Total active intervention delivery time: ~3.5 hours Participants are provided with self-management resources to optimise adherence to the anti-inflammatory diet up to the 6-month follow-up.	Two in-person consultations at baseline (~45 min) and week 12 (~30 min) One phone/videoconference follow-up consultation (30 min) in week 6. Total active control delivery time: ~1.5 hours Participants encouraged to sustain their diet up to 6 month follow-up.
TAILORING	Individualised anti-inflammatory dietary advice, education and support aligning with participant preferences and goals.	Advice based on the ADGs.
MODIFICATIONS	Any modifications will be reported.
HOW WELL (planned)	2–3 professionals (qualified dietitian and other health professional) receive prior training in how to deliver and supervise the programme. Fidelity is assessed through random auditing by members of the principal investigator team (AGC or BLD). Participant adherence to the anti-inflammatory diet is assessed through consultation attendance, regular 3-day food diaries and self-report.	2–3 professionals (qualified dietitian and health professional) receive prior training in how to deliver and supervise the programme. Fidelity is assessed through random auditing by members of the principal investigator team (AGC or BLD). Participant adherence to the standard care low-fat diet is assessed through consultation attendance, regular 3-day food diaries and self-report.
HOW WELL (actual)	This will be reported in the primary paper.

TIDieR, Template for Intervention Description and Replication.;