FIG. 2.

Titration of peptides recognized by the Rev-specific clone TCC108. Chromium-labelled autologous B-LCL cells were incubated with the peptide Rev(65-75) GRSAEPVPLQL, Rev(66-75) RSAEPVPLQL, or Rev(67-75) SAEPVPLQL for 1 h at the concentrations indicated. Subsequently, the target cells were washed and cocultivated with TCC108 cells for 4 h. The effector-to-target cell ratios were 10:1. The average percent specific lysis (with standard error) for triplicates is shown. No lysis of B-LCL cells without peptide was observed (data not shown).