TABLE 2.
Lysis of HIV-1 IIIB-infected cells by CD8+ T cells used in this studya
CD8+ T-cell line | Specificity
|
Effector/target ratio | % Specific lysis (mean ± SD)
|
||
---|---|---|---|---|---|
Protein | Epitope | Mock infection | HIV-1 IIIB infection | ||
TCC108 | Rev | SAEPVPLQL | 10 | 5 ± 4 | 48 ± 6 |
3 | 0 ± 3 | 37 ± 1 | |||
TCC112 | NDb | ND | 10 | −1 ± 1 | 4 ± 2 |
3 | −4 ± 1 | −8 ± 1 | |||
TCL1C11 | RT | IVLPEKDSW | 10 | −1 ± 1 | 63 ± 8 |
3 | −1 ± 1 | 62 ± 9 |
Target cells were CD4+ TCL2H7 cells 10 days after mock or HIV-1 IIIB infection (MOI of approximately 0.05).
ND, not determined.