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. 2024 Mar 7;30(9):1108–1120. doi: 10.3748/wjg.v30.i9.1108

Table 4.

Effectiveness of the four most frequently used treatment regimens against the various symptoms, n (%)


MPA effectiveness, n = 3563
PPI effectiveness, n = 3563
MPA + PPI effectiveness, n = 3563
MPA + PPI + PD effectiveness, n = 3563
P value
Epigastric pain 219 (55.9) 155 (47.7) 751 (66.7) 207 (68.5) < 0.001
Abdominal distension 212 (54.1) 158 (48.6) 608 (54.0) 194 (64.2) 0.001
Postprandial fullness 191 (48.7) 106 (32.6) 455 (40.4) 156 (51.7) < 0.001
Early satiety 144 (36.7) 59 (18.2) 309 (27.4) 103 (34.1) < 0.001
Acid regurgitation 159 (40.6) 102 (31.4) 466 (41.4) 164 (54.3) < 0.001
Nausea 135 (34.4) 61 (18.8) 261 (23.2) 86 (28.5) < 0.001
Belch 168 (42.9) 88 (27.1) 355 (31.5) 152 (50.3) < 0.001
Vomiting 87 (22.2) 38 (11.7) 140 (12.4) 43 (14.2) < 0.001
Others 72 (18.4) 14 (4.3) 42 (3.7) 21 (7.0) < 0.001

MPA: Mucosal protective agent; PPI: Proton pump inhibitor; PD: Prokinetic drug.