Table 4.
|
MPA effectiveness, n = 3563
|
PPI effectiveness, n = 3563
|
MPA + PPI effectiveness, n = 3563
|
MPA + PPI + PD effectiveness, n = 3563
|
P value
|
Epigastric pain | 219 (55.9) | 155 (47.7) | 751 (66.7) | 207 (68.5) | < 0.001 |
Abdominal distension | 212 (54.1) | 158 (48.6) | 608 (54.0) | 194 (64.2) | 0.001 |
Postprandial fullness | 191 (48.7) | 106 (32.6) | 455 (40.4) | 156 (51.7) | < 0.001 |
Early satiety | 144 (36.7) | 59 (18.2) | 309 (27.4) | 103 (34.1) | < 0.001 |
Acid regurgitation | 159 (40.6) | 102 (31.4) | 466 (41.4) | 164 (54.3) | < 0.001 |
Nausea | 135 (34.4) | 61 (18.8) | 261 (23.2) | 86 (28.5) | < 0.001 |
Belch | 168 (42.9) | 88 (27.1) | 355 (31.5) | 152 (50.3) | < 0.001 |
Vomiting | 87 (22.2) | 38 (11.7) | 140 (12.4) | 43 (14.2) | < 0.001 |
Others | 72 (18.4) | 14 (4.3) | 42 (3.7) | 21 (7.0) | < 0.001 |
MPA: Mucosal protective agent; PPI: Proton pump inhibitor; PD: Prokinetic drug.