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. 2024;12(3):149–158. doi: 10.22038/ABJS.2024.68053.3224

Table 2.

Study Characteristics

Author, year Des ign Sample size Subject Criteria Follow-Up Procedure Group Outcomes
Guo et al. 2020 E 45 Big-ear rabbit from Laboratory Animal Research Center of the Hospital 3 weeks Intraparitoneal injection
  • Normal saline

  • BMSCs

  • Sham

  • Triceps weight

  • Amplitudo and latency of CMAP

  • Histopathology nerve tissue with HE Stain

Huanxing et al. 2013 E 24 Adult female Sprague-Dawley rat weight 220 – 250 grams 16 weeks Musculocutaneus nerve injection
  • hi-UMC

  • Vehicle injection

  • EMG measurement

  • whole-cell patch-clamp record

  • biceps NMJ

Rodriguez et al. 2021 E 42 Adult male Wistar Lewis rat 335.13 ± 35.71 grams and 80 ± 10 days old 12 weeks Phrenicus transfer with Musculocutaneous graft
  • Autograft

  • ANA

  • ANA + BMSCs

  • Biceps contraction

  • Amplitudo dan latency of CMAP

  • Histological analysis of biceps dan nerve graft with electron microscope and fluorosence

Yang et al. 2019 E 18 Adult male Sprague-Dawley rat weight 200-300 grams six weeks old 16 weeks Contralateral transfer of C7 to C5-C6
  • Autograft

  • ANA

  • ANA + dASCs

  • grooming test

  • Amplitudo of CMAP

  • Nerve IHC analysis

  • Axon density

  • Muscle morphology

E: experimental

BMSCs: bone marrow mesenchymal stem cells

CMAP: compound muscle action potential

hi-UMC: human induced umbilical cord mesenchymal cells

EMG: electromyography

NMJ: neuromuscular junction

ANA: acellular nerve allograft

dASCs: differentiated adipose stem cells

IHC: immunohistochemistry