Figure 4.

Marginal effects evaluation. Based on the data in reference [70], the marginal effects of the four biomes (Gut, Lake, Soil, Fermentor) on all the 8700 unknown Pfam families (version 32.0) were evaluated, described in reference [70]. The background is an ontology structure that contains the protein families and their relationships, while different colors indicated the high marginal effect values for that protein family by a certain biome. The marginal effect values are also annotated beside several proteins of interest. The data show that the contributions of different biomes to a specific Pfam can be drastically different, as reflected by their marginal values