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A proposed catalytic mechanism of DsyB. (A) The schematic diagrams of the DsyB conformational change triggered by the binding of SAM. (B) The sulfur atom of MTHB attacks on the methyl group of SAM to generate DMSHB and SAH. The MTHB molecule and DMSHB molecule are shown in black. And the SAM molecule and the SAH molecule are shown in red.
