Figure 7.
Intratumoral microbiota might activate carcinogenic pathways. (A) Dot plot showing the top 10 pathways enriched in MS1 using KEGG enrichment analysis in different clustering situations. The size of the dot represents the gene counts contributing to the pathway. (B) Enrichment plots showing increased expression of cell cycle and p53 signaling pathway gene sets in MS1 cohort. Stacked bar plot showing χ 2 test of (C) C1A/C1B cluster, (D) mRNA cluster, (E) methylation cluster proportions between MS1 and MS2 in NR clustering.