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Metabolic methods used in tumor microbiome research. (A) Microbial metabolites affecting tumors through a variety of mechanisms. (B) Three most commonly used approaches of tumor microbe metabolomic research: nuclear magnetic resonance (NMR), liquid chromatography mass spectroscopy (LC‐MS) with multiple reaction monitoring (MRM), and gas chromatography mass spectroscopy (GC‐MS) with selection ion monitoring (SIM).
