Author response image 2. We analyzed transposons located in introns, genes, downstream (ds) or upstream (us) of genes (distance to gene < 25 kb) or in intergenic regions (distance to gene > 25 kb).

Independent of their location, transposons show similar differential expression with aging or cellular senescence (A). In contrast, the expression of transposons (log counts) is highly dependent on their location and the median log(count) value decreases in the order: genic > intronic > ds > us > intergenic.