Table 2.

Association of fibroids with breast cancer, stratified by race/ethnicity

			Age Adjusted	Partially Adjusted	Fully Adjusted
	Person-Years	Breast Cancer Events	HR (95% CI)1	HR (95% CI)1	HR (95% CI)1
non-Black women (includes non-Hispanic White women, Hispanic women, and other non-Black women)
Fibroids
No Fibroids	29,501	2,609	Ref	Ref	Ref
Fibroids	15,018	1,439	1.05 (0.99 to 1.12)	1.04 (0.98 to 1.11)	1.07 (1.00 to 1.15)
Fibroids +/− Surgery
No Fibroids	29,501	2,609	Ref	Ref	Ref
Fibroids Without Surgery	6,861	658	1.09 (1.00 to 1.19)	1.07 (0.98 to 1.16)	1.06 (0.97 to 1.16)
Fibroids With Hysterectomy Only	3,080	333	1.16 (1.04 to 1.31)	1.13 (1.01 to 1.27)	1.17 (1.04 to 1.31)
Fibroids With Bilateral Oophorectomy	5,078	448	0.94 (0.85 to 1.04)	0.95 (0.86 to 1.05)	0.97 (0.87 to 1.08)
Non-Hispanic Black / African American women
Fibroids
No Fibroids	1,561	121	Ref	Ref	Ref
Fibroids	2,420	250	1.30 (1.04 to 1.62)	1.31 (1.05 to 1.64)	1.34 (1.07 to 1.69)
Fibroids +/− Surgery
No Fibroids	1,561	121	Ref	Ref	Ref
Fibroids Without Surgery	1,037	103	1.31 (1.01 to 1.71)	1.32 (1.01 to 1.73)	1.34 (1.02 to 1.75)
Fibroids With Hysterectomy Only	708	77	1.35 (1.01 to 1.80)	1.34 (1.00 to 1.80)	1.37 (1.02 to 1.85)
Fibroids With Bilateral Oophorectomy	675	70	1.23 (0.91 to 1.66)	1.26 (0.92 to 1.71)	1.24 (0.90 to 1.71)
Wald Test for Heterogeneity of association between fibroids and breast cancer by race/ethnicity
p-value			0.12	0.10	0.08

¹HR = Hazard Ratio, CI = Confidence Interval