Table 2.

Psychopathological symptoms measure according to the predicted CYP2D6 phenotype.

Symptom measure	EMs(N = 36)	IMs (N = 25)	Unknowns(N = 15)	Statistics	Adjusted P valuea
PANSS total score
Week 0-Week 2	11.33 ± 8.49	11.80 ± 11.03	10.87 ± 9.13	0.047	0.955
Week 0-Week 4	20.20 ± 9.09	19.45 ± 14.12	19.21 ± 13.18	0.048	0.953
Week 0-week 8	29.93 ± 11.69	28.65 ± 17.60	27.78 ± 15.99	0.113	0.893
PANSS-positive subscale total score
Week0-week 2	5.81 ± 3.42	4.64 ± 5.23	5.27 ± 3.15	0.609	0.547
Week0-week 4	10.74 ± 4.49	10.86 ± 6.37	9.21 ± 5.69	0.487	0.616
Week0-week 8	13.60 ± 4.70	14.00 ± 6.15	12.64 ± 5.12	0.279	0.757
PANSS-negative subscale total score
Week0-week 2	3.00 ± 4.79	4.24 ± 5.29	3.30 ± 4.82	0.765	0.469
Week0-week 4	7.29 ± 6.03	6.77 ± 8.85	5.71 ± 6.32	0.248	0.781
Week0-week 8	5.93 ± 7.03	6.65 ± 7.86	10.36 ± 7.12	0.523	0.595
PANSS-general subscale total score
Week 0-week 2	2.53 ± 6.59	2.92 ± 5.60	3.13 ± 7.51	0.055	0.946
Week 0-week 4	2.17 ± 7.52	1.82 ± 9.11	3.85 ± 7.19	0.284	0.753
Week 0-week 8	11.45 ± 8.41	8.00 ± 8.19	4.78 ± 9.93	0.870	0.424

Abbreviations: EMs, Extensive metabolizers; IMs, Intermediate metabolizers; PANSS, Positive and Negative Syndrome Scale.

^aAdjusted P value after sex correction.