Table 3.
Univariate and multivariate COX regression models for predicting progression-free survival
| Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | |
| Gender, male |
/ (/–/) |
0.385 | ||
| Tumor subsite | ||||
| Oropharynx | 1 (Reference) | |||
| Hypopharynx | 1.24 (0.56–2.74) | 0.601 | ||
| Neoadjuvant cycle | ||||
| 3 | 1 (Reference) | |||
| Others | 0.91(0.44–1.91) | 0.810 | ||
| Best overall response | ||||
| ORR | 1 (Reference) | |||
| Stable disease + progressive disease | 1.58 (0.75–3.30) | 0.226 | ||
| T stage change | ||||
| Down | 1 (Reference) | 1 (Reference) | ||
| Same | 2.29 (1.07–4.92) | 0.033 | 1.50 (0.63–3.58) | 0.364 |
| N-stage change | ||||
| Down | 1 (Reference) | 1 (Reference) | ||
| Same | 2.70 (1.04–7.02) | 0.042 | 1.15(0.22–6.10) | 0.874 |
| AJCC-stage change | ||||
| Down | 1 (Reference) | 1 (Reference) | ||
| Same | 3.15 (1.22–8.16) | 0.018 | 3.15 (1.22–8.16) | 0.018 |
ORR objective response rate