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. 2023 Oct 14;72(12):4209–4219. doi: 10.1007/s00262-023-03557-6

Table 3.

Univariate and multivariate COX regression models for predicting progression-free survival

Univariate analysis Multivariate analysis
HR (95% CI) P HR (95% CI) P
Gender, male

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0.385
Tumor subsite
 Oropharynx 1 (Reference)
 Hypopharynx 1.24 (0.56–2.74) 0.601
Neoadjuvant cycle
 3 1 (Reference)
 Others 0.91(0.44–1.91) 0.810
Best overall response
 ORR 1 (Reference)
 Stable disease + progressive disease 1.58 (0.75–3.30) 0.226
T stage change
 Down 1 (Reference) 1 (Reference)
 Same 2.29 (1.07–4.92) 0.033 1.50 (0.63–3.58) 0.364
N-stage change
 Down 1 (Reference) 1 (Reference)
 Same 2.70 (1.04–7.02) 0.042 1.15(0.22–6.10) 0.874
AJCC-stage change
 Down 1 (Reference) 1 (Reference)
 Same 3.15 (1.22–8.16) 0.018 3.15 (1.22–8.16) 0.018

ORR objective response rate