Table 1.

Cytotoxic effects of compounds on human cancer and normal cell lines

Comp	IC50(μΜ)a
	HepG2	LO2	SIb
Ir	37.13 ± 2.20	46.45 ± 2.63	1.27
PVI	> 100	> 100	–
PVIS-OH	> 100	> 100	–
PVIG-OH	> 100	> 100	–
Ir:PVI	13.81 ± 1.03	39.85 ± 5.84	2.88
PVIS-Ir	1.82 ± 0.18	26.54 ± 1.52	14.58
PVIG-Ir	1.99 ± 0.10	21.78 ± 1.79	10.95

^aIn vitro cytotoxicity was determined by MTT assay upon incubation with the compounds for 72 h. Mean values were obtained upon three independent experiments

^bSelectivity Index = IC₅₀ (LO2)/IC₅₀ (HepG2)