Table 1.
Surface marker | Cell type | GBM | AA | AO | |||
---|---|---|---|---|---|---|---|
Median | 95% CI | Median | 95% CI | Median | 95% CI | ||
CD45 + | Hematopoietic cells | 1024,977 | 101,278 | 362,000 | 645,721 | 335,870 | 162,195 |
CD14-CD3 + | T cell | 262,696 | 63,817 | 151,000 | 191,113 | 142,606 | 47,199 |
CD4 + | CD4 + T cell | 105,000 | 27,542 | 19,043 | 114,850 | 63,261 | 26,029 |
CD4 + FoxP3 + CD25 + | Regulatory CD4 + T cell | 8972 | 2914 | 1,221 | 11,973 | 697 | 1910 |
CD4 + FoxP3-CD25- | Non-regulatory CD4 + T cell | 87,793 | 24,368 | 14,648 | 102,728 | 60,600 | 22,605 |
CD8 + | CD8 + T cell | 126,846 | 32,655 | 74,800 | 56,041 | 70,767 | 18,273 |
CD14-CD3-CD19 + | B cell | 9,975 | 6,595 | 21,500 | 9,120 | 12,700 | 8,243 |
CD14-CD3-CD56 + | NK cell | 9,485 | 4,130 | 6,000 | 6,524 | 12,759 | 12,213 |
CD14-CD3-CD11c + | Dendritic cell | 152,000 | 26,999 | 194,000 | 49,896 | 118,000 | 39,564 |
CD14 + | Monocyte/Macrophage | 146,139 | 34,717 | 17,578 | 433,029 | 26,087 | 38,406 |
CD163 + | M2-monocyte/macrophage | 46,872 | 16,592 | 11,600 | 364,412 | 7,510 | 20,227 |
CD68 + | TAM | 10,296 | 2642 | 338 | 1,625 | 163 | 8369 |
CD68 + CD163 + | M2-TAM | 5678 | 1424 | 145 | 342 | 89 | 4494 |
GBM glioblastoma, AA anaplastic astrocytoma, AO anaplastic oligodendroglioma, CI confidence interval, TAM Tumor-associated macrophage