Fig. 2.

Upregulation TIGIT expression on both CD3⁻CD56^hi and CD3⁻CD56^dim NK cells in AML patients. Representative histogram of TIGIT expression on CD3⁻CD56^hi a and CD3⁻CD56^dim b NK cells. Quantification of frequency (top) and MFI (bottom) of TIGIT expression on NK subsets including CD45⁺CD3⁻CD56^hi c and CD45⁺CD3⁻CD56^dim NK cells d from HD and AML patients by flow cytometry. Each symbol represents one subject, and the data are shown as the mean (± SEM). HD, healthy donors. P values, unpaired two-tailed t-test (a, b, c, d), *P < 0.05, ***P < 0.001