Fig. 3.

TIGIT expressing NK cells with dysfunctional phenotype from AML patients. TIGIT + NK cells were first gated and then the frequency and MFI of CD96 a, PD-1 b, TIM-3 c, CD200R d, CD226 e, NKG2D f expression on these cells from AML patients and HDs were quantified. Each symbol represents one subject, and the data are shown as the mean (± SEM). HD, healthy donors. P values, unpaired two-tailed t-test (a, b, c, d), *, P < 0.05; **, P < 0.01; ***, P < 0.001. ns, no significant difference