Fig. 2. Results of eQTL annotation and PGS association testing.

A Gene-based phenogram of eQTL annotations for the exploratory-level findings of the ImmuneSet in ConLi⁺Gen. Those eQTL genes that were different from the mapped gene and those that were the same are presented in circle and diamond shapes, respectively. Only protein-coding genes are shown. In addition, overlaps with BP genetic associations reported in the GWAS Catalog are presented. B Exploratory findings from the association analyses of immune-related polygenic scores and BP phenotypes in ConLi⁺Gen “GWAS1”. The heatmap shows the estimates (scaled by column) obtained for each PGS-phenotype pair. Increasing color darkness alludes to increasing effect, with red and blue colors representing positive and negative values, respectively. *p < 0.05, **p < 0.01.