Table 4.
Prioritized ImmuneSet candidate genes for Li response and clinical characteristics in ConLi+Gen.
| Gene | Chr | Start | End | Priority | Phenotypes |
|---|---|---|---|---|---|
| ALK | 2 | 29415640 | 30144432 | Psychiatric | Depression, Mania |
| NRXN1 | 2 | 50145643 | 51259674 | Psychiatric | Depression, Hypomania, Substance |
| RTN4 | 2 | 55199325 | 55339757 | Psychiatric | Mania, Psychosis |
| CNTNAP5 | 2 | 124025287 | 124915287 | Li response | LiResponse, Alda_B, Alda_Total |
| LRP1B | 2 | 140988992 | 142889270 | Psychiatric | AAO, Mania |
| ROBO2 | 3 | 75906695 | 77649964 | Both | Alda_Total, Hypomania, Substance |
| BANK1 | 4 | 101411286 | 102074812 | Both | Continuous.LiResp, Alda_A, Alda_B, Alda_Total, Hypomania |
| CDH12 | 5 | 21750673 | 22853622 | Both | LiResponse, Suicide |
| DSP | 6 | 7541575 | 7586717 | Li response | Continuous.LiResp, Alda_Total |
| NPSR1-AS1 | 7 | 34386124 | 34911194 | Psychiatric | Depression, Suicide |
| CNTNAP2 | 7 | 146116002 | 148420998 | Both | LiResponse, Alda_Total, Mania |
| NRG1 | 8 | 31496902 | 32622548 | Psychiatric | Mania, Substance |
| XKR4 | 8 | 56014949 | 56454613 | Psychiatric | Depression, Mania, Psychosis, Substance |
| NFIB | 9 | 14081843 | 14398983 | Li response | Continuous.LiResp, Alda_B |
| NRG3 | 10 | 83635070 | 84746935 | Psychiatric | Alcohol, Psychosis |
| BMPR1A | 10 | 86756601 | 86932838 | Li response | Continuous.LiResp, Alda_A |
| GRK5 | 10 | 120967101 | 121215131 | Psychiatric | AAO, Depression |
| FAT3 | 11 | 92352096 | 92896470 | Both | LiResponse, Alda_Total, Depression |
| PCDH9 | 13 | 66302834 | 67230445 | Both | Alda_B, Mania, Substance |
| CPPED1 | 16 | 12756919 | 12897874 | Psychiatric | AAO, Depression |
| HAS3 | 16 | 69105564 | 69118719 | Li response | Continuous.LiResp, Alda_A, Alda_Total |