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. 2024 Apr 3;15(4):243. doi: 10.1038/s41419-024-06617-6

Fig. 3. Bioenergetics profiles of erythroblasts isolated from iPD patients’ and age-matched healthy controls.

Fig. 3

Galactose medium was used to force energetic metabolism through OXPHOS and to unmask mitochondrial defects. A In glucose conditions, PD patients display reduced basal and maximal oxygen consumption rate (compare dark and light blue boxes). Galactose medium increases OCR in PDerythroblasts (compare light blue and orange boxes), but not in cells from healthy controls (compare dark blue and red boxes). B ECAR is reduced in galactose medium. *P < 0.05, **P < 0.01, ***P < 0.001; one-way ANOVA followed by Tukey’s multiple comparison test.