Table 1.

Correlation between TMERS and clinicopathological factors of glioma patients in the three datasets

Characteristics	TCGA dataset			CGGA dataset			GSE16011 dataset
	Low-risk group (n = 351)	High-risk group (n = 351)	P-Value	Low-risk group (n = 162)	High-risk group (n = 163)	P-Value	Low-risk group (n = 134)	High-risk group (n = 134)	P-Value
Age
Mean(range)	41 (17–74)	54 (21–89)	< 0.001	39 (10–75)	47 (8–81)	< 0.001	46 (15–81)	56 (14–79)	< 0.001
Gender
Female	126	129	n.s	65	57	n.s	46	42	n.s
Male	176	178		97	106		88	92
NA	49	44		0	0		0	0
Grade
II	175	41	< 0.001	92	13	< 0.001	21	3	< 0.001
III	127	114		39	37		64	21
IV	0	152		31	113		49	110
NA	49	44		0	0		0	0
IDH status
Mutant	336	92	< 0.001	141	35	< 0.001	57	23	< 0.001
Wildtype	5	229		21	128		51	85
NA	10	30		0	0		26	26
1p/19q status
Codel	150	19	< 0.001	62	5	< 0.001	39	7	< 0.001
Non-codel	193	302		97	153		33	55
NA	8	30		3	5		62	72
MGMT promoter
Methylated	317	160	< 0.001	90	68	< 0.05	NA	NA
Unmethylated	26	136		62	87		NA	NA
NA	8	55		10	8		NA	NA
TCGA subtype
Proneural	190	48	< 0.001	85	17	< 0.001	87	8	< 0.001
Neural	74	37		65	16		17	9
Classical	0	86		11	63		22	36
Mesenchymal	0	95		1	67		8	81
NA	87	85		0	0		0	0