Table 1.
Patient characteristics
| Baseline characteristics (N = 68) | |
|---|---|
| Median age (range)—year | 68 (40–84) |
| Male sex, N (%) | 61 (89.7%) |
| ECOG performance status score—N (%) | |
| 0 | 14 (20.6%) |
| 1 | 54 (79.4%) |
| Smoking statusa—N (%) | |
| Never smoker | 3 (4.4%) |
| Current smoker | 38 (55.9%) |
| Former smoker | 27 (39.7%) |
| Brain metastases at baseline—N (%) | 17 (25.0%) |
| PCI | 4 (6.0%) |
| Previous treatment for LS-SCLC | 2 (3.0%) |
| PD-L1 statusb | |
| ≥ 1 | 2 (3.0%) |
| < 1 | 45 (66.2%) |
| Unknown | 21 (30.9%) |
ECOG Eastern Cooperative Oncology Group, PCI prophylactic cranial irradiation, LS-SCLC limited-stage small-Cell lung cancer, PD-L1 programmed death-ligand 1
aA current smoker was defined to be an individual who currently smokes or has quit for < 1 year, a former smoker was an individual who had stopped smoking for > 1 year, and a never smoker was an individual with a lifetime smoking history of < 100 cigarettes
bThe PD-L1 tumor proportion score was defined as the percentage of tumor cells with membranous PD-L1 expression