Table 4.
Treatment response to the first and second cycles of induction chemotherapy between the two groups.
| Response/n (%) |
DNMT3A-mutated /CD7+(n=21) |
Non-DNMT3Amut/CD7+(n=276) | p value |
|---|---|---|---|
| First cycle | 0.306 | ||
| CR/CRi | 10 (47.6) | 172 (62.3) | |
| PR | 6 (28.6) | 49 (17.8) | |
| NR | 5 (23.8) | 55 (19.9) | |
| Second cycle | 0.003 | ||
| CR/CRi | 12 (57.1) | 221 (80.1) | |
| PR | 6 (28.6) | 17 (6.2) | |
| NR | 3 (14.3) | 38 (13.8) | |
| Relapse | 9 (75.0) | 88 (39.8) | 0.032 |
CR, complete remission; CRi, CR with incomplete hematologic recovery; PR, partial remission; NR, no remission.