Table 1.
Characteristics | TCGA-LUAD (Training set) | GSE30219 (Validation set 1) | GSE31210 (Validation set 2) | ||||
---|---|---|---|---|---|---|---|
Number of cases | Percent % | Number of cases | Percent % | Number of cases | Percent % | ||
Total | 459 | 83 | 225 | ||||
Age | > 60 | 314 | 68.4 | 46 | 55.4 | 118 | 52.4 |
≤ 60 | 145 | 31.6 | 37 | 44.6 | 107 | 47.6 | |
Gender | Male | 214 | 46.6 | 65 | 78.3 | 104 | 46.2 |
Female | 245 | 53.4 | 18 | 21.7 | 121 | 53.8 | |
Pathological Stage | Stage I | 249 | 54.2 | 167 | 74.2 | ||
Stage II | 111 | 24.2 | 58 | 25.8 | |||
Stage III | 78 | 17 | 0 | 0 | |||
Stage IV | 21 | 4.6 | 0 | 0 | |||
Tstage | T1 | 158 | 34.4 | 69 | 83.1 | ||
T2 | 243 | 52.9 | 12 | 14.5 | |||
T3 | 41 | 9 | 2 | 2.4 | |||
T4 | 17 | 3.7 | 0 | 0 | |||
Nstage | N0 | 302 | 65.8 | 80 | 96.4 | ||
N1 | 88 | 19.2 | 3 | 3.6 | |||
N2 | 67 | 14.6 | 0 | 0 | |||
N3 | 2 | 0.4 | 0 | 0 | |||
Mstage | M0 | 83 | 100 | ||||
M1 | 0 | 0 | |||||
EGFR mutation | Mutation | 126 | 56 | ||||
Wild-type | 99 | 44 | |||||
KRAS mutation | Mutation | 20 | 8.9 | ||||
Wild-type | 205 | 91.1 |