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. 2021 Oct 11;71(5):1183–1197. doi: 10.1007/s00262-021-03066-4

Table 1.

Clinical characteristics of LUAD patients in training and validation cohorts

Characteristics TCGA-LUAD (Training set) GSE30219 (Validation set 1) GSE31210 (Validation set 2)
Number of cases Percent % Number of cases Percent % Number of cases Percent %
Total 459 83 225
Age > 60 314 68.4 46 55.4 118 52.4
≤ 60 145 31.6 37 44.6 107 47.6
Gender Male 214 46.6 65 78.3 104 46.2
Female 245 53.4 18 21.7 121 53.8
Pathological Stage Stage I 249 54.2 167 74.2
Stage II 111 24.2 58 25.8
Stage III 78 17 0 0
Stage IV 21 4.6 0 0
Tstage T1 158 34.4 69 83.1
T2 243 52.9 12 14.5
T3 41 9 2 2.4
T4 17 3.7 0 0
Nstage N0 302 65.8 80 96.4
N1 88 19.2 3 3.6
N2 67 14.6 0 0
N3 2 0.4 0 0
Mstage M0 83 100
M1 0 0
EGFR mutation Mutation 126 56
Wild-type 99 44
KRAS mutation Mutation 20 8.9
Wild-type 205 91.1