Fig. 4.

Association between CD47 mRNA expression and tumor-intrinsic genomic features. a Quantification analyses of normalized CD47 mRNA expression in GSE62254 database across molecular classification systems (n = 300). Data were analyzed by one-way ANOVA, and presented as median and interquartile range (IQR). b Quantification of molecular subtype signatures between low/high CD47 mRNA expression subgroup (n = 300). Data were analyzed by Student’s t test, and presented as median and IQR. c Association of genes mutation frequency with CD47 mRNA expression level (n = 181). Data were analyzed by Chi-square test. d Quantification analyses of therapy-associated gene signatures between low/high CD47 mRNA expression subgroup (n = 300). Data were analyzed by Student’s t test, and presented as median and IQR. *P < 0.05, **P < 0.01, ***P < 0.001, and NS indicates not significant