Fig. 2.

Kaplan–Meier Plot of Progression-Free Survival Abbreviations: Inf.U = infectious units; PD-1/L1 = programmed death 1/programmed death ligand 1; RECIST = Response Evaluation Criteria In Solid Tumors. Legend: Cohort 1 = First-line treatment, ineligible for cisplatin-containing chemotherapy. Cohort 2 = Second-line treatment, previously treated with standard first-line cisplatin-based chemotherapy, PD-1/L1 inhibitor naïve. The figure includes all subjects who received any amount of trial vaccine, whether MVA-BN-CV301 alone or followed by FPV–CV301. Kaplan–Meier method estimates were used to create the figure. Time to progression included progression per Investigator assessment using modified RECIST v1.1 or death due to any cause. Subjects were censored at the last radiographic scan, which indicated no progression if the endpoint had not occurred for the subject